Author: Karen Lennox
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minutes
Last Updated:
August 08, 2022
Chinese researchers may be key to the discovery of an oral drug to treat type 2 diabetes and obesity.
As is well known, the two diseases go hand in hand - being overweight contributes to the development of type 2 diabetes. Research has focused on a compound called Boc5, which alone is not effective enough for type 2 diabetes and obesity, but researchers speculate that its derivatives will lead to the creation of the next generation of antidiabetic drugs - the so-called incretin mimetics. These drugs resemble the intestinal peptide GLP1.
These medicines will help patients with type 2 diabetes to normalize their blood sugar, lose weight and improve their insulin secretion. So far, clinical trials have been conducted with a drug from this group with the generic name liraglutide, but the problem with it is the long chain, which makes it difficult to produce in oral form and is required as an injectable preparation.
What makes Boc5 different is the small molecule and is therefore promising as a substrate for the production of a new, potent, oral antidiabetic agent that will also lead to weight loss.