Author: Joe Fowler
Time for reading: ~1
minutes
Last Updated:
August 08, 2022
Scientists have identified a component in green tea that prevents the formation of beta-amyloid plaques in the brain.
A new study has been able to identify a specific ingredient in green tea, the substance epigallocatechin gallate (EGCG). Chemically, it belongs to the group of polyphenols and from the observations of researchers it is clear that it has the ability to disrupt the formation of toxic beta-amyloid plaques .
B eta-amyloid plaques are deposited in the brain in Alzheimer's disease. They disrupt the proper functioning of the connections between neurons and various parts of the brain and thus cause the described symptoms.
Alzheimer's disease is a progressive neurodegenerative disease known for its damage - weakening of memory and the ability to think, as well as changes in gait.
Previous studies have linked green tea to a reduced risk of Alzheimer's disease, but they have so far failed to elucidate the mechanism of these observations.
The described observations not only confirm the previous studies suspecting the preventive role of EGCG, but also reveal the specific mechanisms of this beneficial effect.
A building block of plaques are beta-amyloid monomers, which together form oligomers (several linked monomers). Using magnetic resonance imaging, the team found that the substance EGCG remodels beta-amyloid oligomers, preventing them from forming plaques.
Despite the promising results, the team notes that providing EGCG access to the brain is currently a problem. Therefore, the continuation of this study will focus on developing methods for overcoming the obstacle.
It is known that any damage to the brain is irreversible and therefore at this stage the main emphasis in the behavior of this disease is prevention and prevention - the aim of doctors is to slow down the course of the disease and delay the worsening of symptoms.