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Where Did That Even Come From?

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In the 80s, a team of respected Norwegian researchers suggested a unusual locating. They had been evaluating the urine of autistic kids to the urine of regular children, in hope of teasing out any variations that could result in recommendations as to what the cause is.

This is a urine profile, which suggests spikes for each of the various components.

This is what ordinary urine comes out like, with the peptides area quite quiet. (Peptides are like small portions of proteins, and commonly, we shouldn’t be peeing out tons protein).

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But that is the urine profile from a child with autism, with all kinds of peptide spikes.

Here’s every other one. This raised the query:

“Can the Pathophysiology [the dysfunction] of Autism be Explained with the aid of the Nature of the[se] Discovered Urine Peptides?” First, they had to response:

“Where do the peptides come from?” They didn’t understand.

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But, there was a clue:

most of the dad and mom of autistic kids said that they were given worse after they had been uncovered to cow’s milk.

Huh? Well, there are those two proteins:

gluten, a protein in wheat, and casein, a protein in milk, that wreck down not most effective into peptides, however exorphins.

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Exorphins are “opioid peptides derived from food proteins”—”referred to as exorphins…because of their exogenous beginning [meaning from outside of the body] and morphine-like interest,” as opposed to endorphins, which can be morphine-like compounds we deliver inside our bodies. So, maybe some of those meals peptides represent like “A New Class of Hormones?” So, is that what the kids have been peeing out?

Apparently so, as some of those peptides had opioid interest.

Okay. So, perhaps they were onto some thing.

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There are “[t]wo sorts of opioids [that] have been located within milk.” One is the “casomorphins within view in their morphine-like interest and their starting place.” They are breakdown products, fragments of the milk protein casein.

What’s the alternative one? The other opioid is the actual opiate:

morphine.

There seems to be real morphine within milk.

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This can’t just be a coincidence.

“It is [hard] to agree with that those, or other sorts of opioids discovered within the milk, are devoid of physiological or dietary significance.” And, reflect onconsideration on it;

it makes overall feel. “Morphine and the opioid peptides might also…have an essential position in the mom-little one bond…” We want toddlers to be “’addicted’ to their own mother’s milk.” Okay.

But, What About The Milk Of Another Species?

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“Human [breast] milk is markedly one of a kind from that of other…species [in that it] has the lowest” casein content material, and human casein is a markedly unique protein in terms of its sequence of amino acid constructing blocks. Human milk has 15 instances much less casein than bovine milk, and differs collection-clever by way of about 1/2, and so breaks down into peptides differently.

Twenty-one bioactive peptides have been recovered from cow casein, which include multiple casomorphins, compared to handiest five active peptides diagnosed in human milk, and handiest one casomorphin.

And, the casomorphins “from bovine casein are more potent.” This is a image of opioid interest, where decrease way stronger. Here’s the potency of heterosexual morphine.

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