Is There A Genetic Predisposition To Obesity

I don't eat anything, but I'm still getting fat! It is enough just to look at the sweets, and immediately +2 kg! Who has not heard this from people who are forever losing weight and complain that they have thick bones? And maybe we ourselves are like that. Why can someone eat everything and stay in great shape, while others, despite restrictions and physical activity, slowly part with excess weight or cannot lose weight at all? According to some nutritionists, the answer to this question may lie in the so-called obesity genes , which contribute to weight gain . Let's try to figure out whether there is still a genetic predisposition to excess weight ?

FTO

The obesity gene , or FTO (fat mass and obesity associated), is associated with the formation of satiety hormones - leptin and ghrelin. With a large amount of these hormones in the body, a person quickly feels satiety, with a lack - he can eat and not feel full for another 30-40 minutes, which encourages him to eat more.

MC4R

The MC4R gene is responsible for appetite. Through this receptor, a signal is sent to the brain to suppress the feeling of hunger and stop eating. If there is a malfunction in this gene , the probability of developing obesity increases. When the feeling of satiety does not come for a long time, a person can eat a lot, which as a result leads not only to a feeling of heaviness, but also to excess weight . The desire to satisfy hunger will intensify, arise earlier, in the end you will always want to eat. If you consume extra calories and do not have time to spend them in time, excess weight cannot be avoided.

In this regard, a high-protein diet works well because protein gives us the main satiety. Accordingly, porridge with fruit for breakfast is no longer suitable. It is necessary to add protein omelets, poultry, fish to the diet or add vegetable protein (legumes).

To keep your weight under control, always try to eat slowly, chew your food thoroughly, and enjoy the taste and aroma.

FABP2

The FABP2 gene (fatty acid binding protein 2) is responsible for the assimilation of animal fats (meat, butter, dairy products, cottage and hard cheese, sour cream). It happens that even if you eat very small portions of food, the weight keeps increasing. In this case, attention should be paid to the FABP2 gene .

Under a normal scenario, the body should absorb only half of the fats, that is, in general, about 2.5% of the fat will be absorbed from 100 g of 5% sour-milk cheese. But if there is a malfunction in the gene , then all 5% can be assimilated.

Accordingly, to keep weight under control, you need to eat almost 2 times less animal fats. Controlling the amount of fat consumed is also important because animal products are rich in cholesterol. And a person with a broken FABP2 gene will not only intensively gain excess weight from exposure to animal fats, but will also quickly face health problems caused by poor nutrition and high blood cholesterol levels.

CD36

Someone likes fatty food, and someone does not. A possible reason here should be sought in the work of the receptor - CD36. It is responsible for sensitivity and attachment to fats in food: a failure in the CD36 gene will manifest itself in a strong craving for fatty food, and, accordingly, will contribute to excess weight.

The more failures in the genes responsible for weight , the higher the risk of overeating and obesity .

ADRB3

The ADRB3 gene (β3-adrenoceptor) is responsible for fat loss in response to physical activity. It happens that even with regular sports, excess weight is not lost. Why does this happen? The culprit may not be a bad trainer or a lack of motivation, but the work of the ADRB3 gene , which, when malfunctioning, interferes with weight loss.

If glycogen (glucose stores) is slowly consumed from the muscles, then, most likely, you have problems with the ADRB3 gene : in order not to gain weight , you need to add intensive training to your routine and control the amount of carbohydrates consumed in the evening.

As you can see, genetic predisposition to overweight and obesity still exists . But even with such features, you can learn to keep your body in good shape. The main thing is to understand how the human body, and yours personally, is arranged, how and what you can influence, and start following these rules. Positive results will not make you wait a long time.