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Otherwise, the steady estrogen signaling should eventually bring about endometrial cancer.

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In truth, perhaps that’s why menopause evolved: to guard the uterus from cancer.

Lower estrogen stages are also good for decreasing breast cancer danger.

“In postmenopausal ladies, quite high [blood] levels of [estrogen] are associated with a greater than [double] growth[d] risk for breast cancer.” Estrogen stages drop 95% at menopause, but now not to zero, due to the fact other tissues can make estrogen—like our very own fats cells. “[T]his likely explains the increase within [breast cancer] hazard within obese postmenopausal women.” More fatty tissue means extra estrogen manufacturing.

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Now, we discovered that soy phytoestrogens can block the production of estrogen, such that consuming a tumbler of soy milk with each meal can reduce estrogen stages in half in premenopausal women.

But degrees in postmenopausal women are already down 95%, and because of that, many girls be afflicted by hot flashes.

Might Lowering Levels Even Further With Soy Make Menopausal Symptoms Even Worse?

Estrogen treatment could be very powerful within decreasing menopausal signs.

Unfortunately, the downside isn't always simplest the uterine most cancers, however blood clots, strokes, “and cognitive impairment.” Taking progesterone-type compounds with the estrogen allows prevent the uterine most cancers, however will increase the chance of coronary heart attacks;

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extra stroke hazard, breast most cancers, greater clots, and dementia.

So, what’s a girl to do?

Well, the 80% warm flashes determine isn't always general; perhaps “80-85% within European and American women,” however it may be as low as just 15% within places like Japan.

In truth, there’s now not even a word for it within the Japanese language, which helps how relatively rare it's miles.

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Maybe the phytoestrogens in soy are helping? “The affiliation among soy product intake and the prevalence of hot flashes turned into examined” through following a thousand Japanese women earlier than they commenced menopause, through the years, to look who evolved warm flashes and who didn’t.

And, the ones ladies who have been consuming like four oz of tofu a day appeared to cut their chance within 1/2, in comparison to girls who best ate like an oz. or two an afternoon— suggesting soy products are “protecting.” But, maybe soy consumption is just a marker for a more healthy diet prevalent?

A research in China discovered the intake of “entire plant ingredients” within fashionable regarded to be associated with decreased menopausal signs and symptoms. So, to see if soy turned into some thing special, you’d should positioned it to the take a look at.

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Studies like this, of soy phytoestrogens within tablet shape, showed incredible outcomes—a great drop in hot flash presence, wide variety, and severity.

From 100% of ladies struggling at the beginning, to only 31% struggling through the give up of three months. The average number of warm flashes dropped from approximately 120 a month right down to 12.

But, the trouble with reviews like these is that there’s no manipulate organization to manipulate for the placebo effect.

If you examine all the hormone trials, even the ladies who were given the placebo sugar pills had as much as a 60% reduction within warm flashes through the years.

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That’s why any therapy “alleged to lessen such symptoms should be assessed within blinded trials against a placebo…because of the big placebo effect…and also due to the fact…menopaus[al] signs often decline” on their own over the years.

So, if you noticed a study like this, where they gave ladies a soy protein powder, and saw a pleasant drop within warm flashes over the next 12 weeks, you’d suppose it appears pretty effective—but that’s the placebo powder group.

Here’s the institution that were given the soy—extensively better than placebo. But, it’s crucial to understand how effective the placebo effect may be.

Over the past two decades, “greater than 50 [clinical] trials have evaluated the results of soy foods and [supplements] at the comfort of warm flashes.” Compiling the quality ones collectively, the placebo groups got approximately a 20% drop in warm flash severity.

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The soy businesses achieved about a 45% drop. So, on average, the soy did about 25% higher than manipulate.

There were reviews that in comparison soy phytoestrogens head-to-head in opposition to hormones.

And, in one poll, they really seemed pretty similar within phrases of reducing warm flashes, muscle and joint ache, and vaginal dryness, in comparison to placebo—even though in the different, soy did better than placebo. But estrogen and progesterone therapy did better than them each.

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