Why Do Women Gain Weight With Age?

Author: Marko Balašević Time for reading: ~1 minutes Last Updated: August 08, 2022

According to experts, weight gain is due to the increased activity of the enzyme Aldh1a1.

One of the most terrifying moments for any woman with advancing age is gaining weight, especially after menopause .

According to experts, weight gain is due to the increased activity of the enzyme Aldh1a1 , which stimulates the accumulation of fat around the internal organs, the so-called. visceral adipose tissue.

This is closely linked to the risk of type 2 diabetes , cardiovascular disease and cancer.

In addition to menopause, the enzyme increases its activity in the consumption of fatty and high-calorie foods, researchers from the University of Ohio explain.

They found that estrogen , a female sex hormone, suppresses the action of the enzyme Aldh1a1 and regulates the accumulation of visceral adipose tissue.

After menopause, however, estrogen levels fall sharply, making it difficult to regulate Aldh1a1. Retinoic acid begins to be produced , which leads to the formation of visceral adipose tissue.

Estrogen is a female sex hormone produced by the ovaries. It is associated with ovulation and sexual behavior in women. Estrogenic hormones are estrone, estriol, estradiol.

According to Dr. Oliana Ziozenkova, an assistant professor of human nutrition at Ohio University, this genetic factor cannot be controlled by increasing physical activity and changing diet alone . This may help, but not solve the problem.

Discovering this relationship, the research team hopes to develop a method aimed at suppressing the enzyme and reducing obesity in postmenopausal women and beyond.

The results of the study were published in the journal Diabetes .

Why Do Women Gain Weight With Age?

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