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They have been basically denied, with the FDA saying that the evidence was “very restrained and preliminary,” without a endorsement allowed for ketchup or supplements.

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By that point, further population experiences had solid doubt on the lycopene theory. Consumers of high dietary intakes of lycopene didn’t appear to have lower cancer shares, after all.

But, who has high dietary intakes of lycopene?

Those that eat the most pizza; so, maybe it’s no wonder there are combined outcomes.

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What we need is to put lycopene to the check.

It started out with a case study. A 62-yr old man with terminal prostate cancer;

failed surgical operation, failed chemotherapy, metastases all over, unfold to the bone.

And so, he become despatched to hospice to die.

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So, he took it upon himself to provoke “phytotherapy”—plant-primarily based remedy, taking the quantity of lycopene found within a quarter-cup of tomato sauce, or a tablespoon of tomato paste each day.

His PSA, a degree of tumor bulk, began out at 365, dropped to 140 the following month, after which down to 8.

His metastases commenced disappearing, and, as of his final comply with-up, appeared to be residing happily ever after. But, whilst given in better-dose pill shape, it didn’t seem to work.

A 2013 assessment of all such lycopene complement trials “did not support [the initial] optimism.” In truth, they were just glad that the lycopene capsules didn’t become inflicting extra most cancers, like beta-carotene tablets did.

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But, then got here 2014. Researchers within Italy have been giving the most important doses they could of lycopene, selenium, and remoted inexperienced tea compounds to guys with precancerous prostate lesions, hoping they might save you full-blown cancer.

But, within 2014, the increased consequences of a comparable trial were published, wherein selenium and diet E supplements ended in greater most cancers.

Yikes! So, these researchers stopped their trial, and broke the code to unblind the consequences, And certainly, the ones taking high doses of lycopene, inexperienced tea catechins, and selenium seemed to get extra most cancers than folks that just got sugar drugs.

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“The potential implications are dramatic,” said the lead researcher, “given the contemporary huge international use of such compounds as alleged preventive supplementations in prostate and other cancers.” What went incorrect?

Well, after the beta-carotene tablet debacle, researchers measured mobile harm at unique herbal and unnatural doses of beta-carotene. At nutritional doses, beta-carotene suppressed cell damage, but at higher, supplemental doses, it not best regarded to stop running, but caused more damage.

And, the identical with lycopene.

“Both lycopene and [beta]-carotene afforded safety towards DNA harm” at the styles of levels one would possibly see in people eating plenty of tomatoes or candy potatoes—”levels…similar with the ones visible inside the [blood] of those who consume a carotenoid-rich healthy food plan.” However, on the type of blood concentrations that one would possibly get taking drugs, “the capability to shield the cells towards such [free radical] harm changed into rapidly lost, and, indeed, the presence of [high levels of beta-carotene and lycopene] may without a doubt serve to increase the volume of DNA harm.” So, no surprise excessive-dose lycopene capsules didn’t paintings.

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“Phytochemicals [may be] guardians of our fitness,” but “[t]he protection of ingesting concentrated extracts…is unknown.” The shielding blessings of a phytochemical-rich weight loss program is pleasant acquired [through whole plant foods].” The food industry has distinctive thoughts, even though.