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They have been essentially denied, with the FDA saying that the proof became “very limited and preliminary,” with out a endorsement allowed for ketchup or supplements.

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By that point, similarly population studies had forged doubt on the lycopene concept. Consumers of excessive nutritional intakes of lycopene didn’t appear to have decrease most cancers rates, in the end.

But, who has high dietary intakes of lycopene?

Those that eat the most pizza; so, perhaps it’s no marvel there are mixed outcomes.

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What we need is to position lycopene to the check.

It started with a case study. A 62-12 months vintage man with terminal prostate most cancers;

failed surgical treatment, failed chemotherapy, metastases throughout, unfold to the bone.

And so, he changed into sent to hospice to die.

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So, he took it upon himself to initiate “phytotherapy”—plant-based totally therapy, taking the amount of lycopene located within 1 / 4-cup of tomato sauce, or a tablespoon of tomato paste every day.

His PSA, a measure of tumor bulk, commenced out at 365, dropped to 140 the next month, and then all the way down to 8.

His metastases commenced disappearing, and, as of his last comply with-up, appeared to be residing luckily ever after. But, when given in higher-dose tablet shape, it didn’t appear to work.

A 2013 assessment of all such lycopene supplement trials “didn't aid [the initial] optimism.” In truth, they were simply happy that the lycopene pills didn’t turn out to be causing greater cancer, like beta-carotene pills did.

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But, then came 2014. Researchers within Italy have been giving the most important doses they might of lycopene, selenium, and isolated green tea compounds to guys with precancerous prostate lesions, hoping they might save you full-blown cancer.

But, within 2014, the increased consequences of a similar trial have been posted, wherein selenium and nutrition E supplements resulted in greater cancer.

Yikes! So, those researchers stopped their trial, and broke the code to unblind the effects, And indeed, the ones taking high doses of lycopene, green tea catechins, and selenium seemed to get extra most cancers than folks that just were given sugar tablets.

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“The potential implications are dramatic,” said the lead researcher, “given the cutting-edge huge international use of such compounds as alleged preventive supplements within prostate and other cancers.” What went incorrect?

Well, after the beta-carotene tablet debacle, researchers measured mobile damage at unique herbal and unnatural doses of beta-carotene. At nutritional doses, beta-carotene suppressed cellular harm, however at better, supplemental doses, it no longer simplest appeared to stop running, but triggered greater damage.

And, the same with lycopene.

“Both lycopene and [beta]-carotene afforded safety in opposition to DNA damage” on the types of tiers one may see within human beings ingesting lots of tomatoes or candy potatoes—”levels…comparable with the ones visible within the [blood] of folks who consume a carotenoid-wealthy healthful weight-reduction plan.” However, at the form of blood concentrations that one would possibly get taking pills, “the capacity to defend the cells in opposition to such [free radical] damage changed into hastily lost, and, indeed, the presence of [high levels of beta-carotene and lycopene] can also honestly serve to boom the quantity of DNA harm.” So, no marvel excessive-dose lycopene tablets didn’t paintings.

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“Phytochemicals [may be] guardians of our health,” however “[t]he safety of eating concentrated extracts…is unknown.” The defensive blessings of a phytochemical-wealthy weight-reduction plan is quality acquired [through whole plant foods].” The food enterprise has specific thoughts, though.