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Where Did That Even Come From?

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In the 80s, a team of respected Norwegian researchers reported a unusual locating. They have been evaluating the urine of autistic kids to the urine of regular youngsters, in hope of teasing out any differences that would lead to pointers as to what the purpose is.

This is a urine profile, which depicts spikes for each of the various additives.

This is what regular urine comes out like, with the peptides region pretty quiet. (Peptides are like small pieces of proteins, and generally, we shouldn’t be peeing out an awful lot protein).

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But that is the urine profile from a infant with autism, with all forms of peptide spikes.

Here’s any other one. This raised the question:

“Can the Pathophysiology [the dysfunction] of Autism be Explained by means of the Nature of the[se] Discovered Urine Peptides?” First, they needed to answer:

“Where do the peptides come from?” They didn’t understand.

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But, there was a clue:

most of the mother and father of autistic youngsters pronounced that they got worse once they were exposed to cow’s milk.

Huh? Well, there are those proteins:

gluten, a protein in wheat, and casein, a protein in milk, that break down now not only into peptides, however exorphins.

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Exorphins are “opioid peptides derived from meals proteins”—”known as exorphins…due to their exogenous foundation [meaning from outside of the body] and morphine-like hobby,” rather than endorphins, which might be morphine-like compounds we offer inner our our bodies. So, maybe a number of those meals peptides represent like “A New Class of Hormones?” So, is that what the youngsters were peeing out?

Apparently so, as some of those peptides had opioid hobby.

Okay. So, perhaps they were onto some thing.

There are “[t]wo types of opioids [that] had been found within milk.” One is the “casomorphins within view in their morphine-like activity and their starting place.” They are breakdown merchandise, fragments of the milk protein casein.

What’s the alternative one? The different opioid is the real opiate:

morphine.

There seems to be actual morphine in milk. This can’t just be a twist of fate.

“It is [hard] to accept as true with that those, or different types of opioids observed inside the milk, are without physiological or nutritional significance.” And, reflect onconsideration on it;

it makes total experience. “Morphine and the opioid peptides may…have an essential role within the mother-toddler bond…” We want infants to be “’addicted’ to their very own mother’s milk.” Okay.

But, what approximately the milk of every other species?

“Human [breast] milk is markedly distinct from that of other…species [in that it] has the lowest” casein content, and human casein is a markedly specific protein within phrases of its series of amino acid constructing blocks. Human milk has 15 instances much less casein than bovine milk, and differs sequence-smart by means of about half, and so breaks down into peptides in another way.

Twenty-one bioactive peptides had been recovered from cow casein, inclusive of more than one casomorphins, in comparison to best five energetic peptides identified within human milk, and handiest one casomorphin.

And, the casomorphins “from bovine casein are stronger.” This is a picture of opioid pastime, in which decrease way stronger. Here’s the potency of hetero morphine.