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“…[I]nterest in shark cartilage as an anticancer agent arose due to the fact many human beings believed that sharks did now not get cancer.” Why would they think such a factor?

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Because a few shark-cartilage supplement hawker wrote a book referred to as Sharks Don’t Get Cancer. But that’s truely no longer true.

“Sharks do get cancer.” “…[B]oth benign and cancerous…lesions had been suggested in 21 species of sharks from [more than] 9 families.” For instance, this oral tumor spilling out of the mouth of this extraordinary white.

Now, a few “shark cartilage vendors insist [instead] that sharks [just] hardly ever get most cancers,” [but] actual most cancers shares in sharks have [never] been determined.” “[T]right here [has simply] been no systematic tumor surveys of sharks” for them to make the sort of declare. But appearance, “although sharks [were] much less vulnerable to cancer,” how can one logically leap from that to most cancers patients cashing in on eating powdered cartilage from a shark?

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“We realize, as an instance, that there are [certain] proteins that allow [some bacteria to survive] within boiling warm [springs].” Uh, does that suggest if we consume the ones bacteria we can survive boiling water, too?

It doesn’t make any sense. “The illogic behind the pursuit of shark cartilage therapies has implications beyond the discount of shark populations and the misdirection of sufferers to useless cancer treatment plans.” The stuff may be dangerous, and i’m no longer simply talking about the rare case of “shark cartilage-caused liver [inflammation].” Shark merchandise can incorporate the neurotoxin BMAA, which I’ve pointed out earlier than.

It’s been detected at accelerated stages inside the brains of Alzheimer’s ailment and ALS patients, and may “play…a role in [the development of] neurodegenerative illnesses.” So, the “intake of shark-fin soup may additionally pose a enormous fitness risk.” But what about shark-cartilage supplements?

They examined 16 industrial shark-cartilage dietary supplements, proper off the shelves, and found BMAA “in fifteen out of sixteen.” But appearance, even though shark-cartilage dietary supplements deliver “pro-inflammatory residences, which could pose a capability fitness danger for clients,” we’re speakme about most cancers.

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There are chemotherapy dealers which might be existence-threateningly dangerous, however from time to time the advantages can outweigh the dangers, whilst confronted with most cancers.

So, the query then becomes:

are there any advantages to shark cartilage? I imply, it’s now not a completely wacky concept.

“[C]artilage [in general] is incredibly proof against invasion with the aid of tumor cells.” So, maybe there’s a few “cartilage-derived anti-invasion element.” “Less exciting alternative motives…are” that it’s simply hard for the cancer to penetrate the cartilage, or possibly because of the negative blood deliver within cartilage, most cancers doesn’t keep in mind it specifically fertile ground.

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But perhaps that loss of blood vessels within cartilage may be exploited. The purpose that no blood vessels come to be in cartilage is due to the fact cartilage cells deliver angiogenesis inhibitors, blood vessel-advent inhibitors.

So, maybe we will starve tumor increase through infusing these cartilage factors.

What scientists do is implant tumors into the eyeballs of rabbits, as a way to visualize what number of blood vessels the tumor is capable of draw to itself. And, certainly:

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“Shark cartilage incorporates inhibitors of tumor angiogenesis.” “Such findings made the income [of shark cartilage sky]rocket, [driving]…two shark species…to the brink of extinction.” But, cow cartilage does the same issue.

Here, they used bovine cartilage. And so does human cartilage, for that matter.

So, why sell shark cartilage?

Well, it does sound a lot more exotic, and sharks have like 10 times extra cartilage in step with animal.

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One 20-foot shark should internet like 50 pounds of cartilage.

Just because cartilage has blood vessel-inhibiting chemicals within it, even though, doesn’t imply if most cancers sufferers devour it, it will help them.

It’s type of like magical thinking: shark cartilage stops blood-vessel increase.

“Thus, with the aid of consuming shark cartilage, humans will [somehow] be…protected.” I suggest, the “shark cartilage protein molecules [would seem to be] too large to be absorbed by the intestine.” It’s not like you’re injecting shark cartilage into your bloodstream thru an IV.

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But there has been this rat statistic that did find that simply feeding shark cartilage to the animals, you may reduce down on blood vessel boom through their our bodies.

Okay, But Does That Translate Out To Stopping The Growth And Spread Of Cancer?

Apparently not, as “not one of the shark cartilage doses tested had any retarding effect on [cancer growth]” or spread in tumor-bearing mice.

But simply because it doesn’t paintings in rodents doesn’t imply it doesn’t work within human beings.