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Where Did That Even Come From?

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In the 80s, a team of respected Norwegian researchers suggested a weird locating. They had been comparing the urine of autistic kids to the urine of everyday children, in wish of teasing out any variations that would cause guidelines as to what the purpose is.

This is a urine profile, which suggests spikes for each of the numerous additives.

This is what everyday urine comes out like, with the peptides area quite quiet. (Peptides are like small pieces of proteins, and normally, we shouldn’t be peeing out a good deal protein).

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But that is the urine profile from a baby with autism, with all styles of peptide spikes.

Here’s every other one. This raised the query:

“Can the Pathophysiology [the dysfunction] of Autism be Explained by way of the Nature of the[se] Discovered Urine Peptides?” First, they needed to answer:

“Where do the peptides come from?” They didn’t recognize.

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But, there has been a clue:

most of the dad and mom of autistic kids mentioned that they were given worse when they were exposed to cow’s milk.

Huh? Well, there are these proteins:

gluten, a protein within wheat, and casein, a protein within milk, that damage down now not most effective into peptides, but exorphins.

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Exorphins are “opioid peptides derived from food proteins”—”known as exorphins…because of their exogenous beginning [meaning from outside of the body] and morphine-like hobby,” in preference to endorphins, which are morphine-like compounds we provide interior our bodies. So, maybe some of these meals peptides constitute like “A New Class of Hormones?” So, is that what the kids were peeing out?

Apparently so, as a number of the ones peptides had opioid pastime.

Okay. So, maybe they had been onto something.

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There are “[t]wo varieties of opioids [that] were discovered in milk.” One is the “casomorphins in view of their morphine-like interest and their origin.” They are breakdown merchandise, fragments of the milk protein casein.

What’s the opposite one? The other opioid is the real opiate:

morphine.

There appears to be real morphine within milk.

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This can’t just be a twist of fate.

“It is [hard] to consider that those, or other varieties of opioids found in the milk, are devoid of physiological or nutritional importance.” And, reflect onconsideration on it;

it makes overall feel. “Morphine and the opioid peptides may also…have an essential role inside the mother-little one bond…” We need babies to be “’addicted’ to their personal mother’s milk.” Okay.

But, What About The Milk Of Another Species?

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“Human [breast] milk is markedly distinct from that of different…species [in that it] has the bottom” casein content material, and human casein is a markedly one-of-a-kind protein in terms of its sequence of amino acid building blocks. Human milk has 15 instances less casein than bovine milk, and differs sequence-smart with the aid of about 1/2, and so breaks down into peptides in another way.

Twenty-one bioactive peptides had been recovered from cow casein, together with multiple casomorphins, as compared to best five active peptides recognized within human milk, and only one casomorphin.

And, the casomorphins “from bovine casein are stronger.” This is a graph of opioid activity, wherein lower method stronger. Here’s the efficiency of hetero morphine.

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