Lycopene B

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But, lycopene in complement form doesn’t appear like effective at lower doses, both.

Lycopene Benefits For Skin

“There is a strong [protective] correlation among the consumption of [actual whole] fruit[s] and veggies and the occurrence of sure cancers.” But when we supplement with handiest a single compound isolated within tablet shape, we might also disenchanted the wholesome natural stability of antioxidants. It does appear to be quite the human hubris to think we will reproduce “the beneficial effects of consuming complete culmination and veggies” by way of giving supplements of a single phytochemical, which could normally interact with lots of other compounds in “the herbal matrix” Mother Nature supposed.

In addition to lycopene, other carotenoids within tomatoes consist of beta-carotene, gamma-carotene, zeta-carotene, phytofluene, and phytoene, all of which are acknowledged “to accumulate within human prostate tissue.” And, “there also are numerous non–carotenoid compounds in tomatoes that [may] have [anti-cancer] interest”—now not to mention all the compounds we have but to even characterize.

But, it’s not approximately finding the only magic bullet: “The anti-cancer outcomes of carotenoids and different phytonutrients can also live within [their] blended interest.” For example, on the low concentrations of the tomato compounds phytoene, phytofluene, and lycopene determined within most people who eat ordinary amounts of tomatoes, there’s very little effect on most cancers mobile increase in vitro, used one after the other.

Lycopene Benefit

But integrate all of them together, and a non-powerful dose plus a non-powerful dose will become powerful one way or the other, drastically suppressing prostate cancer mobile boom.

And, the equal synergy may be seen across foods. Curcumin, the yellow pigment within turmeric and curry powder, tomato extracts, and the diet E located within nuts and seeds do little to inhibit pro-growth signaling of prostate most cancers cells—less than 10%.

But all three together suppresses growth signaling like 70%.

The whole is greater than the sum of its elements.

Lycopene Benefits For Eyes

So, How About Instead Of Giving Cancer Patients Lycopene Pills, We Give Them Some Tomato Sauce?

“Thirty-two sufferers with localized prostate [cancer]” have been given three-quarters of a cup of canned tomato sauce every day “for 3 weeks…earlier than their scheduled radical prostatectomy.” In their bloodstream, PSA tiers dropped “by using 17.5%.” PSA, prostate-unique antigen, is a protein produced by prostate gland cells, and accelerated blood ranges are robotically used “to display the fulfillment of [cancer] remedy.

It became surprising to locate that,” in just three weeks, a “tomato sauce-based totally dietary intervention” could lower PSA concentrations within men with prostate cancer. Also, unfastened radical harm of the DNA in their white blood cells dropped by using 21%.

Imagine how antioxidant-negative their weight loss program ought to had been ahead, if less than a cup of tomato sauce a day should lessen DNA harm by using more than a 5th.

Lycopene Benefits Prostate

Okay, however what did they locate of their prostates? “[H]uman prostate tissue [is thought to] be in particular at risk of oxidative DNA damage by way of loose radicals, which might be thought to play a essential function in all stages of [cancer formation].” This can be for a number of motives, along with “fewer DNA restore enzymes.” Well, the researchers had tissue samples taken earlier than the tomato sauce from biopsies, and tissue samples after the 3 weeks of tomato sauce from the surgical procedure, and resected tissues from tomato sauce-supplemented patients had 28% much less unfastened radical harm than predicted.

Here’s the DNA harm in the prostate before the tomato sauce, and here’s after.

Just 20 days of sauce. And, what’s interesting is that “[t]right here was no association among” the extent of lycopene in the prostate and the protective results.

Lycopene Benefits For Hair

Tomatoes comprise an entire bunch of things, some of which may be even extra powerful than lycopene.

Regardless, in contrast to the lycopene supplements on my own, “the entire-food intervention” seemed to assist. To see if lycopene performed any function in any respect, one might have to check a lycopene-loose tomato—in other phrases, a yellow tomato.

So, what in case you in comparison red tomatoes to yellow tomatoes, which have all the non-lycopene tomato compounds, to directly lycopene within a pill?

So, they fed people crimson tomato paste, yellow tomato paste, lycopene tablets, or placebo pills, and then dripped their blood on prostate cancer cells developing in a petri dish.

Lycopene Beta Carotene

Compared to those now not ingesting something, the red tomato serum, the blood from folks that ate pink tomato paste, drastically reduced the prostate most cancers mobile’s expression of a increase-selling gene known as cyclin D1.

This downregulation of the gene via the crimson tomato consumption “may additionally contribute to lower prostate most cancers hazard through limiting cellular proliferation.” The crimson tomato seemed to paintings higher than the yellow;

so, maybe the lycopene helped, but now not within tablet shape. “[T]his gene turned into no longer regulated via [the lycopene-pill serum],” indicating that perhaps it’s something else.

And, lycopene by myself substantially upregulated “procarcinogenic genes.

Lycopene Benefits For Sperm