Author: Victoria Aly
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Last Updated:
February 11, 2026
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Polycystic ovary syndrome can be “the most not unusual [hormonal] abnormality” among young girls within the United States, a common reason of infertility, menstrual dysfunction, and extra facial and body hair.
So, What We Eat Maybe Is Only Indirectly Related To Pcos, Through Weight Gain?
No, due to the fact the identical link among high AGE stages and PCOS was found within lean women, as properly. “As chronic inflammation and expanded [oxidative] stress had been incriminated within the [disease process] of PCOS, the role of AGEs as [pro-]inflammatory and [pro-]oxidant mediators may additionally [indeed] be linked with the metabolic and reproductive abnormalities of the syndrome.” And, in addition, the buildup of AGE inside polycystic ovaries themselves suggests “a potential position of ages” contributing to the sickness process itself, past simply a number of the consequences.” “RAGE [is] tremendously expressed” within ovarian tissues.In other words, the receptor—that’s the R in RAGE—the receptor in the frame for those superior glycation give up merchandise—is focused, for some cause, in the ovaries.
So, ovaries may be mainly touchy to their results. So, AGEs may indeed be contributing “to the motive of polycystic ovary syndrome…and infertility.” So, must we just reduce down on meat, cheese, and eggs?Or, we are able to always give you AGE absorption-blocking off tablets.
We know that “AGEs have been implicated within the development of many” chronic illnesses.Indeed, reducing down on these dietary glycotoxins “reduces the inflammatory response.” But, stewed bird just doesn’t taste as suitable as fried bird.
So, therefore, you may have your KFC and devour it, too. Just take this drug with it every time you consume, to cut down on the absorption of these toxins. And, it really works—it sincerely lowers AGE blood degrees.This oral absorbent drug, AST-120, is only a coaching of activated charcoal.
You understand, there’s some other manner you can reduce your absorption—by lowering your consumption inside the first region.
Simple, secure, and viable. The first issue you do is prevent smoking.The glycotoxins in cigarette smoke “may make a contribution to” the increase of coronary heart disease and most cancers among people who smoke. Then, you may lower your intake of excessive-AGE foods, while growing your intake of foods that could assist pull AGEs from your device, like brown rice and mushrooms.
And, we can eat foods high within antioxidants, like berries, herbs, and spices. “Dietary AGE intake can be…reduced [even just by] converting the approach of cooking” from the high temperature dry cooking methods to low warmness, better humidity.In different phrases, transferring away from “broiling, searing, [and frying” to greater “stewing, steaming, and boiling.” But, what we devour can be extra important than how we cook it.
For example, boiled chook has less than half of the glycotoxins of roasted bird.And, we will stay faraway from excessive-AGE processed ingredients, consisting of puffed, shredded, and flaked breakfast cereals.
Why does it depend? Because research after statistic has shown that switching a person to a low-AGE weight loss plan can lower the infection in their our bodies.Even only a unmarried high-AGE meal can profoundly impair our artery feature through simply hours of consumption.
simply distinct cooking methods.
Now, you’ll note that even the steamed or boiled chook meal nonetheless impaired arterial function. So, you can simply select to eat even healthier, but notably higher than the fried or broiled.Ironically, “the quantity of AGEs administered throughout this [high-AGE] HAGE intervention,” the profoundly-impair-your-artery-characteristic quantity of a while, “become similar to the average envisioned every day consumption by way of the general population,” the Standard American Diet.
That’s why you could decrease irritation within humans, putting them on a low-AGE weight loss program. But, an boom within inflammation changed into much less obvious whilst people switched from their ordinary food regimen to a high-AGE eating regimen, due to the fact they’re already eating a high-AGE eating regimen, so many of these glycotoxins of their everyday eating regimen.
Do We Have Evidence That Reducing Age Intake Actually Helps With Polycystic Ovaries?
Yes.transfer to a high-AGE weight loss plan, to a low-AGE weight loss plan, and you see parallel changes within insulin sensitivity, oxidative pressure, and hormonal popularity, with the take domestic being that those with PCOS may additionally want to attempt a low-AGE weight loss plan, which inside the poll meant proscribing meat to as soon as a week that’s handiest boiled, poached, stewed or steamed, and cutting out fast meals-type meals and soda.
What About Instead Of Steamed Chicken, We Ate No Meat At All?
Rather than measuring blood tiers, which vary with each meal, like if you simply ate a few roasted nuts or something, we can measure the level of glycotoxins stuck on your body tissues over time as a substitute, with a elaborate gizmo that measures the amount of light your skin offers off, due to the fact AGEs are fluorescent.And so, no surprise, this seems to be a sturdy predictor of widely wide-spread mortality.