Metabolic Syndrome Is Provoked By Overeating, Not Obesity
Author: Mark Velov
Time for reading: ~0
minutes
Last Updated:
January 27, 2026
Regular overeating, not the obesity it leads to, is the cause of the development of metabolic syndrome. The latter includes insulin resistance to type 2 diabetes, hypercholesterolemia, hypertension, visceral obesity, etc.,
Regular overeating, not the obesity it leads to, is the cause of the development of metabolic syndrome. The latter includes insulin resistance to type 2 diabetes, hypercholesterolemia, hypertension, visceral obesity, etc., which are high risk factors for the cardiovascular system.
A study of laboratory mice at Texas Southwestern Medical University in Dallas showed that obesity did not cause all of these abnormalities, as previously thought. It itself is an early symptom of the metabolic syndrome. In the experiment, mice were genetically modified to protect against the accumulation of fat in fat cells. After 7 weeks of heavy eating, normal mice developed a metabolic syndrome on the background of obesity. Genetically modified people have remained weak, but signs of metabolic disorders were present much earlier - only a few weeks later. Significant damage to the heart cells as well as insulin-producing ones in the pancreas has been found.
Metabolic syndrome is extremely common worldwide. Improper nutrition and sedentary lifestyle are at the heart of its etiology.
A study of laboratory mice at Texas Southwestern Medical University in Dallas showed that obesity did not cause all of these abnormalities, as previously thought. It itself is an early symptom of the metabolic syndrome. In the experiment, mice were genetically modified to protect against the accumulation of fat in fat cells. After 7 weeks of heavy eating, normal mice developed a metabolic syndrome on the background of obesity. Genetically modified people have remained weak, but signs of metabolic disorders were present much earlier - only a few weeks later. Significant damage to the heart cells as well as insulin-producing ones in the pancreas has been found.
Metabolic syndrome is extremely common worldwide. Improper nutrition and sedentary lifestyle are at the heart of its etiology.
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