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They have been basically denied, with the FDA pronouncing that the proof became “very limited and initial,” with out a endorsement allowed for ketchup or supplements.

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By that time, similarly population reviews had solid doubt on the lycopene theory. Consumers of excessive dietary intakes of lycopene didn’t seem to have decrease cancer shares, in any case.

But, who has high nutritional intakes of lycopene?

Those that devour the most pizza; so, maybe it’s no marvel there are blended outcomes.

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What we want is to put lycopene to the check.

It commenced with a case poll. A 62-12 months antique guy with terminal prostate most cancers;

failed surgical treatment, failed chemotherapy, metastases throughout, unfold to the bone.

And so, he turned into despatched to hospice to die.

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So, he took it upon himself to initiate “phytotherapy”—plant-based totally remedy, taking the quantity of lycopene found in a quarter-cup of tomato sauce, or a tablespoon of tomato paste each day.

His PSA, a degree of tumor bulk, began out at 365, dropped to 140 the subsequent month, and then down to 8.

His metastases began disappearing, and, as of his closing follow-up, appeared to be dwelling fortuitously ever after. But, while given within better-dose tablet shape, it didn’t seem to paintings.

A 2013 assessment of all such lycopene supplement trials “failed to help [the initial] optimism.” In fact, they have been just glad that the lycopene drugs didn’t end up causing more most cancers, like beta-carotene tablets did.

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But, then came 2014. Researchers in Italy were giving the largest doses they could of lycopene, selenium, and remoted inexperienced tea compounds to guys with precancerous prostate lesions, hoping they may prevent full-blown most cancers.

But, in 2014, the accelerated effects of a comparable trial had been posted, wherein selenium and nutrition E dietary supplements ended in extra most cancers.

Yikes! So, those researchers stopped their trial, and broke the code to unblind the results, And certainly, the ones taking excessive doses of lycopene, green tea catechins, and selenium regarded to get greater cancer than those who simply got sugar drugs.

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“The capability implications are dramatic,” stated the lead researcher, “given the contemporary massive global use of such compounds as alleged preventive vitamins in prostate and different cancers.” What went incorrect?

Well, after the beta-carotene pill debacle, researchers measured mobile damage at different herbal and unnatural doses of beta-carotene. At nutritional doses, beta-carotene suppressed mobile harm, however at higher, supplemental doses, it now not simplest seemed to forestall operating, however precipitated more harm.

And, the same with lycopene.

“Both lycopene and [beta]-carotene afforded protection towards DNA damage” on the kinds of stages one would possibly see in people consuming plenty of tomatoes or candy potatoes—”ranges…comparable with the ones seen within the [blood] of individuals who devour a carotenoid-wealthy wholesome food plan.” However, on the type of blood concentrations that one may get taking drugs, “the capability to protect the cells in opposition to such [free radical] damage become rapidly misplaced, and, indeed, the presence of [high levels of beta-carotene and lycopene] may additionally surely serve to increase the extent of DNA damage.” So, no surprise high-dose lycopene tablets didn’t paintings.

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“Phytochemicals [may be] guardians of our health,” but “[t]he protection of consuming concentrated extracts…is unknown.” The defensive advantages of a phytochemical-rich food regimen is satisfactory acquired [through whole plant foods].” The food enterprise has exclusive thoughts, although.