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Although we may also then be stuck with this issue in our mind for existence, our immune machine is so excellent at maintaining it at bay, for maximum healthy humans it’s by no means capable of rear its ugly head—or at the least openly:

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“experiences have now revealed associations among [toxoplasma infection] and the presence of numerous psychiatric problems within human beings”—schizophrenia, bipolar, suicide, self-harm, and memory impairment while we get older. How can a tiny parasite alter our very behavior?

I mentioned how the rabies virus hangs out inside the saliva, while in particular targeting the emotion center of the mind to force animals right into a fury, so they’ll successfully do the virus’s bidding to bite others to transmit the virus;

or the well-known zombie-ant mind fungus that takes over the animal absolutely. These are examples of so-known as parasitic manipulation, in which the parasite manipulates the host to “[enhance] its personal transmission with the aid of changing host behavior.” And toxoplasma is “perhaps one of the maximum convincing examples of a manipulative parasite of [higher animals, like us].” Since the parasite thrives in cats, “chronically infected rodents now not respond to cat odour with worry and certainly the physical answer is reversed to enchantment.” Mice emerge as allured to the odor of cats, serving the parasite up on a silver platter.

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The parasite manipulates the rodent’s mind to turn “their innate aversion to cats into a ‘suicidal’ ‘fatal tom cat enchantment.’” Mice come to be interested in cat pee, and such deadly pussycat enchantment seems specific toward cats.

They don’t emerge as attracted to pee in fashionable. They continue to be detached to rabbit pee, and remain became off by means of other predator pee.

So, on one hand, the parasitic manipulation appears extraordinarily particular, but the parasite doesn’t just need the mouse to are seeking out the cat, but get eaten as nicely.

And so, there are those trendy effects too:

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impaired motor function, slower answer instances, “memory, and co-ordination.” And so, whilst the cat pounces, the parasite attempts to make certain the mouse doesn’t break out.

It’s like whilst California sea otters get toxoplasma, they’re more likely to get eaten by means of a shark.

It’s now not that the parasite desires to get into the shark—it can simply be a by-product of the kind of preferred cognitive deficits this is so useful for the parasite in other contexts. It’s like while human beings get toxoplasma, we start liking the smell of cat pee greater, too.

Isn’t That Wacky?

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The parasite knows simply what strings to drag. But it’s the extra general outcomes we’re worried approximately.

We don’t want to fear our newfound appreciation for saber-enamel tiger urine goes to get us eaten, but mucking with our reaction times, that may be a trouble.

That might be why more than one reports have proven extra traffic and worksite injuries amongst those which are chronically inflamed. But it may no longer simply be our slowed reaction time.

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The parasite seems to additionally affect “diffused behavioural alterations,” like character alterations that make us much more likely to take risks.

Great for the parasite inside the cat-and-mouse sport, but now not a lot if we’re using a vehicle, or wondering whether or not or no longer to take that subsequent drink. Maybe one cause people with this brain parasite get into such a lot of car injuries is that it is able to make human beings have interaction in riskier behaviors, like excessive alcohol intake.

We typically think about malaria as being humanity’s best killer parasite.

“However, whilst we recall the hundreds of heaps of deaths that arise because of the elevated opportunity of visitors injuries, running injuries, suicides, and in all likelihood also other side effects of the infection,” maybe this supposed “’asymptomatic’ latent toxoplasma infection [that has infested one within four Americans] may want to effortlessly take malaria down [a notch].” Before i am getting into a way to save you and deal with the darn thing, what would possibly those different facet outcomes be?

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How precisely does toxoplasma control conduct?

Well, one clue we got decades ago is the upward push in dopamine tiers inside the mind.

You can display it right in a petri dish of infected brain tissue. Turns out that those parasites truly have an enzyme to make dopamine from scratch, which they then launch into the encompassing mind tissue.

Why Do We Care?

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Because elevated dopamine is a feature of schizophrenia. That’s how almost all cutting-edge antipsychotic drugs paintings, by using looking to bring dopamine tiers back off—”either inhibit[ing] dopamine receptors or decreas[ing] the level of dopamine inside the mind.” Is it “possible that the expanded dopamine accumulation and release located all through [toxoplasma] infection” might increase the threat of schizophrenia?

Well, that must be clean to determine out.