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Otherwise, the steady estrogen signaling could subsequently result in endometrial most cancers.

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In truth, maybe that’s why menopause evolved: to defend the uterus from cancer.

Lower estrogen tiers are also properly for lowering breast cancer threat.

“In postmenopausal girls, exceedingly high [blood] tiers of [estrogen] are associated with a greater than [double] increase[d] threat for breast most cancers.” Estrogen stages drop 95% at menopause, however not to zero, because other tissues can make estrogen—like our personal fat cells. “[T]his possibly explains the growth in [breast cancer] chance within overweight postmenopausal women.” More fatty tissue means greater estrogen manufacturing.

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Now, we found out that soy phytoestrogens can block the manufacturing of estrogen, such that ingesting a tumbler of soy milk with every meal can reduce estrogen levels in half in premenopausal girls.

But stages in postmenopausal women are already down 95%, and due to that, many women be afflicted by warm flashes.

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Estrogen remedy is very powerful within decreasing menopausal symptoms.

Unfortunately, the drawback is not simplest the uterine cancer, however blood clots, strokes, “and cognitive impairment.” Taking progesterone-type compounds with the estrogen facilitates prevent the uterine cancer, but will increase the danger of heart assaults;

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extra stroke risk, breast most cancers, greater clots, and dementia.

So, what’s a lady to do?

Well, the 80% hot flashes parent isn't familiar; maybe “80-85% in European and American ladies,” but it can be as low as just 15% in locations like Japan.

In truth, there’s no longer even a word for it inside the Japanese language, which supports how surprisingly rare it's far.

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Maybe the phytoestrogens in soy are helping? “The association among soy product intake and the incidence of warm flashes became tested” with the aid of following a thousand Japanese girls earlier than they started out menopause, over the years, to peer who developed warm flashes and who didn’t.

And, the ones girls who were eating like four ounces of tofu an afternoon appeared to reduce their danger within half of, compared to girls who most effective ate like an oz. or two an afternoon— suggesting soy products are “protecting.” But, perhaps soy intake is just a marker for a healthier food plan well-known?

A statistic within China found the intake of “complete plant ingredients” in standard appeared to be related to decreased menopausal symptoms. So, to see if soy turned into something special, you’d ought to put it to the take a look at.

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Studies like this, of soy phytoestrogens within tablet form, showed first-rate effects—a good sized drop within hot flash presence, quantity, and severity.

From 100% of girls suffering at the beginning, to most effective 31% suffering with the aid of the cease of three months. The average quantity of warm flashes dropped from approximately 120 a month down to 12.

But, the trouble with experiences like these is that there’s no manage institution to govern for the placebo impact.

If you take a look at all of the hormone trials, even the girls who were given the placebo sugar pills had as much as a 60% discount within warm flashes through the years.

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That’s why any remedy “alleged to reduce such symptoms ought to be assessed within blinded trials towards a placebo…due to the huge placebo impact…and also due to the fact…menopaus[al] symptoms frequently decline” on their personal over the years.

So, if you noticed a statistic like this, where they gave ladies a soy protein powder, and saw a nice drop in hot flashes over the subsequent 12 weeks, you’d think it appears pretty powerful—however that’s the placebo powder institution.

Here’s the group that were given the soy—extensively higher than placebo. But, it’s essential to apprehend how effective the placebo effect can be.

Over the beyond two decades, “extra than 50 [clinical] trials have evaluated the effects of soy meals and [supplements] at the alleviation of warm flashes.” Compiling the first-class ones together, the placebo businesses got approximately a 20% drop within warm flash severity.

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The soy groups accomplished approximately a 45% drop. So, on common, the soy did about 25% better than control.

There had been stories that in comparison soy phytoestrogens head-to-head towards hormones.

And, in a single study, they clearly appeared pretty comparable in terms of reducing warm flashes, muscle and joint pain, and vaginal dryness, as compared to placebo—although in the other, soy did higher than placebo. But estrogen and progesterone therapy did better than them each.

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