Author: Dean Rouseberg
Time for reading: ~4
minutes
Last Updated:
August 08, 2022
Learn more information about foods that have antioxidants. In this article we'll discuss foods that have antioxidants.
But, lycopene in supplement form doesn’t look like effective at lower doses, either.
In addition to lycopene, other carotenoids within tomatoes include beta-carotene, gamma-carotene, zeta-carotene, phytofluene, and phytoene, all of which might be recognized “to accumulate in human prostate tissue.” And, “there are also severa non–carotenoid compounds within tomatoes that [may] have [anti-cancer] activity”—no longer to mention all the compounds we have yet to even characterize.
But, it’s now not approximately finding the only magic bullet: “The anti-most cancers consequences of carotenoids and different phytonutrients may additionally are living within [their] mixed interest.” For example, on the low concentrations of the tomato compounds phytoene, phytofluene, and lycopene located in most of the people who devour normal amounts of tomatoes, there’s little or no effect on cancer cell growth in vitro, used one after the other.But combine them all collectively, and a non-powerful dose plus a non-effective dose becomes effective somehow, considerably suppressing prostate most cancers mobile increase.
And, the equal synergy may be seen throughout meals. Curcumin, the yellow pigment in turmeric and curry powder, tomato extracts, and the diet E observed within nuts and seeds do little to inhibit seasoned-growth signaling of prostate cancer cells—less than 10%.But all three together suppresses boom signaling like 70%.
The whole is extra than the sum of its parts.So, How About Instead Of Giving Cancer Patients Lycopene Pills, We Give Them Some Tomato Sauce?
“Thirty- sufferers with localized prostate [cancer]” have been given three-quarters of a cup of canned tomato sauce every day “for 3 weeks…earlier than their scheduled radical prostatectomy.” In their bloodstream, PSA ranges dropped “by means of 17.5%.” PSA, prostate-precise antigen, is a protein produced via prostate gland cells, and expanded blood stages are automatically used “to monitor the achievement of [cancer] treatment.
It become sudden to discover that,” in just three weeks, a “tomato sauce-based nutritional intervention” may want to lower PSA concentrations within guys with prostate cancer. Also, free radical harm of the DNA of their white blood cells dropped via 21%.Imagine how antioxidant-bad their weight loss plan must had been ahead, if less than a cup of tomato sauce a day could lessen DNA harm with the aid of extra than a fifth.
Here’s the DNA damage within the prostate earlier than the tomato sauce, and right here’s after.
Just 20 days of sauce. And, what’s thrilling is that “[t]right here was no association between” the level of lycopene within the prostate and the protective effects.Tomatoes contain a whole bunch of things, a number of which may be even extra effective than lycopene.
Regardless, in assessment to the lycopene supplements on my own, “the complete-meals intervention” appeared to help. To see if lycopene played any position in any respect, one would have to test a lycopene-unfastened tomato—within different words, a yellow tomato.So, what in case you in comparison red tomatoes to yellow tomatoes, which have all the non-lycopene tomato compounds, to straight lycopene within a tablet?
So, they fed human beings pink tomato paste, yellow tomato paste, lycopene capsules, or placebo tablets, after which dripped their blood on prostate cancer cells growing in a petri dish. Compared to the ones not ingesting anything, the crimson tomato serum, the blood from folks that ate pink tomato paste, significantly decreased the prostate cancer cell’s expression of a increase-promoting gene called cyclin D1.This downregulation of the gene by using the red tomato intake “might also make a contribution to decrease prostate cancer threat by way of limiting cell proliferation.” The purple tomato appeared to work better than the yellow;
so, perhaps the lycopene helped, but not in tablet shape. “[T]his gene become now not regulated by [the lycopene-pill serum],” indicating that maybe it’s something else.And, lycopene on my own drastically upregulated “procarcinogenic genes.