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Otherwise, the consistent estrogen signaling should finally result in endometrial cancer.

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In fact, maybe that’s why menopause developed: to defend the uterus from most cancers.

Lower estrogen stages are also excellent for lowering breast cancer hazard.

“In postmenopausal ladies, noticeably excessive [blood] ranges of [estrogen] are related to a greater than [double] increase[d] risk for breast most cancers.” Estrogen degrees drop 95% at menopause, but no longer to zero, because different tissues could make estrogen—like our very own fat cells. “[T]his possibly explains the increase in [breast cancer] chance in overweight postmenopausal women.” More fatty tissue means more estrogen manufacturing.

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Now, we discovered that soy phytoestrogens can block the production of estrogen, such that drinking a tumbler of soy milk with every meal can reduce estrogen levels in half within premenopausal women.

But stages in postmenopausal women are already down 95%, and because of that, many women be afflicted by warm flashes.

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Estrogen remedy is very powerful in decreasing menopausal signs and symptoms.

Unfortunately, the downside isn't most effective the uterine cancer, but blood clots, strokes, “and cognitive impairment.” Taking progesterone-type compounds with the estrogen helps prevent the uterine cancer, but will increase the hazard of heart assaults;

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more stroke danger, breast most cancers, more clots, and dementia.

So, what’s a girl to do?

Well, the 80% hot flashes parent is not customary; perhaps “80-85% within European and American girls,” but it is able to be as little as just 15% in locations like Japan.

In truth, there’s now not even a word for it within the Japanese language, which helps how exceptionally rare it is.

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Maybe the phytoestrogens within soy are supporting? “The association between soy product consumption and the incidence of warm flashes changed into examined” by means of following 1000 Japanese girls before they started menopause, through the years, to peer who evolved warm flashes and who didn’t.

And, the ones women who have been eating like four ounces of tofu a day appeared to reduce their chance within half of, in comparison to ladies who best ate like an ounce or a day— suggesting soy merchandise are “protective.” But, maybe soy intake is only a marker for a more healthy food plan overall?

A poll in China found the consumption of “whole plant foods” in trendy appeared to be related to decreased menopausal symptoms. So, to look if soy was some thing unique, you’d have to placed it to the take a look at.

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Studies like this, of soy phytoestrogens in pill form, showed high-quality results—a substantial drop in warm flash presence, variety, and severity.

From 100% of women struggling at the beginning, to best 31% suffering by using the stop of three months. The average variety of hot flashes dropped from approximately 120 a month down to 12.

But, the trouble with experiences like those is that there’s no manage group to manipulate for the placebo effect.

If you observe all of the hormone trials, even the girls who were given the placebo sugar pills had as much as a 60% reduction in warm flashes over time.

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That’s why any remedy “purported to lessen such signs have to be assessed within blinded trials in opposition to a placebo…because of the huge placebo impact…and additionally because…menopaus[al] signs often decline” on their own over the years.

So, in case you saw a statistic like this, where they gave women a soy protein powder, and saw a pleasing drop within warm flashes over the following 12 weeks, you’d think it appears pretty powerful—but that’s the placebo powder group.

Here’s the institution that got the soy—drastically better than placebo. But, it’s vital to apprehend how effective the placebo effect can be.

Over the beyond twenty years, “more than 50 [clinical] trials have evaluated the outcomes of soy meals and [supplements] at the relief of hot flashes.” Compiling the fine ones collectively, the placebo groups got approximately a 20% drop within hot flash severity.

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The soy organizations executed approximately a forty five% drop. So, on average, the soy did approximately 25% higher than control.

There had been two reviews that as compared soy phytoestrogens head-to-head in opposition to hormones.

And, in one statistic, they absolutely appeared pretty similar within terms of lowering warm flashes, muscle and joint pain, and vaginal dryness, compared to placebo—although inside the different, soy did higher than placebo. But estrogen and progesterone therapy did better than them both.

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