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Otherwise, the regular estrogen signaling should in the end bring about endometrial most cancers.

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In truth, maybe that’s why menopause developed: to defend the uterus from most cancers.

Lower estrogen tiers are also properly for decreasing breast most cancers danger.

“In postmenopausal women, highly high [blood] stages of [estrogen] are associated with a more than [double] boom[d] hazard for breast cancer.” Estrogen levels drop 95% at menopause, but now not to zero, due to the fact different tissues could make estrogen—like our own fats cells. “[T]his probably explains the boom in [breast cancer] danger within overweight postmenopausal girls.” More fatty tissue way extra estrogen manufacturing.

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Now, we discovered that soy phytoestrogens can block the manufacturing of estrogen, such that consuming a pitcher of soy milk with every meal can cut estrogen ranges in half in premenopausal girls.

But levels in postmenopausal girls are already down 95%, and due to that, many women be afflicted by warm flashes.

Might Lowering Levels Even Further With Soy Make Menopausal Symptoms Even Worse?

Estrogen remedy may be very effective in lowering menopausal signs.

Unfortunately, the disadvantage isn't always best the uterine most cancers, but blood clots, strokes, “and cognitive impairment.” Taking progesterone-kind compounds with the estrogen facilitates prevent the uterine cancer, but will increase the chance of coronary heart attacks;

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greater stroke chance, breast cancer, more clots, and dementia.

So, what’s a lady to do?

Well, the 80% warm flashes parent is not standard; maybe “80-85% in European and American girls,” but it could be as low as just 15% within places like Japan.

In fact, there’s now not even a phrase for it within the Japanese language, which supports how noticeably rare it is.

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Maybe the phytoestrogens within soy are assisting? “The affiliation between soy product consumption and the prevalence of hot flashes become tested” with the aid of following a thousand Japanese ladies before they started menopause, through the years, to peer who developed hot flashes and who didn’t.

And, those girls who have been eating like four oz of tofu an afternoon appeared to cut their danger in 1/2, in comparison to ladies who best ate like an oz or two a day— suggesting soy products are “protecting.” But, perhaps soy consumption is just a marker for a more healthy food plan prevalent?

A study within China discovered the intake of “complete plant foods” within trendy appeared to be associated with reduced menopausal signs and symptoms. So, to see if soy become something special, you’d need to placed it to the test.

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Studies like this, of soy phytoestrogens within tablet form, showed high-quality consequences—a full-size drop in hot flash presence, variety, and severity.

From 100% of women struggling at the start, to only 31% suffering with the aid of the end of three months. The common range of hot flashes dropped from approximately 120 a month right down to 12.

But, the hassle with experiences like these is that there’s no manage institution to govern for the placebo effect.

If you look at all the hormone trials, even the girls who got the placebo sugar capsules had up to a 60% reduction within warm flashes over the years.

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That’s why any therapy “presupposed to reduce such signs and symptoms should be assessed within blinded trials in opposition to a placebo…because of the massive placebo effect…and additionally due to the fact…menopaus[al] signs and symptoms often decline” on their own over the years.

So, in case you saw a statistic like this, wherein they gave girls a soy protein powder, and saw a pleasant drop in hot flashes over the subsequent 12 weeks, you’d suppose it looks quite powerful—but that’s the placebo powder organization.

Here’s the group that were given the soy—notably better than placebo. But, it’s critical to recognize how powerful the placebo impact can be.

Over the past 20 years, “more than 50 [clinical] trials have evaluated the results of soy meals and [supplements] on the alleviation of warm flashes.” Compiling the high-quality ones together, the placebo businesses were given about a 20% drop in hot flash severity.

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The soy companies completed about a 45% drop. So, on average, the soy did about 25% better than manage.

There had been reviews that in comparison soy phytoestrogens head-to-head towards hormones.

And, in a single research, they virtually regarded quite similar within phrases of lowering warm flashes, muscle and joint ache, and vaginal dryness, compared to placebo—although inside the other, soy did better than placebo. But estrogen and progesterone therapy did higher than them each.

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