Best Antioxidant Foods

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But, lycopene in supplement form doesn’t look like effective at lower doses, either.

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“There is a sturdy [protective] correlation among the intake of [actual whole] fruit[s] and vegetables and the incidence of certain cancers.” But whilst we complement with only a single compound isolated in pill shape, we might also disenchanted the healthful natural stability of antioxidants. It does seem to be pretty the human hubris to assume we can reproduce “the beneficial results of eating entire culmination and veggies” by means of giving supplements of a single phytochemical, which might generally have interaction with thousands of different compounds in “the natural matrix” Mother Nature meant.

In addition to lycopene, different carotenoids in tomatoes consist of beta-carotene, gamma-carotene, zeta-carotene, phytofluene, and phytoene, all of which are regarded “to build up within human prostate tissue.” And, “there are also severa non–carotenoid compounds in tomatoes that [may] have [anti-cancer] hobby”—now not to mention all of the compounds we've got yet to even signify.

But, it’s no longer approximately finding the one magic bullet: “The anti-cancer results of carotenoids and other phytonutrients may additionally reside within [their] blended pastime.” For example, at the low concentrations of the tomato compounds phytoene, phytofluene, and lycopene found within the majority who eat ordinary quantities of tomatoes, there’s very little impact on cancer cell growth within vitro, used one by one.

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But integrate all of them collectively, and a non-powerful dose plus a non-effective dose will become effective by some means, drastically suppressing prostate most cancers cell boom.

And, the same synergy may be seen across foods. Curcumin, the yellow pigment within turmeric and curry powder, tomato extracts, and the diet E observed within nuts and seeds do little to inhibit seasoned-growth signaling of prostate most cancers cells—less than 10%.

But all three together suppresses growth signaling like 70%.

The complete is more than the sum of its elements.

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So, How About Instead Of Giving Cancer Patients Lycopene Pills, We Give Them Some Tomato Sauce?

“Thirty-two patients with localized prostate [cancer]” have been given three-quarters of a cup of canned tomato sauce each day “for three weeks…before their scheduled radical prostatectomy.” In their bloodstream, PSA degrees dropped “by using 17.5%.” PSA, prostate-unique antigen, is a protein produced by using prostate gland cells, and multiplied blood stages are routinely used “to screen the achievement of [cancer] treatment.

It changed into unexpected to locate that,” in only three weeks, a “tomato sauce-based totally nutritional intervention” should decrease PSA concentrations within guys with prostate most cancers. Also, loose radical harm of the DNA of their white blood cells dropped with the aid of 21%.

Imagine how antioxidant-poor their eating regimen have to have been ahead, if less than a cup of tomato sauce a day could lessen DNA harm by means of extra than a 5th.

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Okay, however what did they find of their prostates? “[H]uman prostate tissue [is thought to] be in particular at risk of oxidative DNA harm with the aid of unfastened radicals, which might be notion to play a important function within all ranges of [cancer formation].” This may be for a number of reasons, consisting of “fewer DNA repair enzymes.” Well, the researchers had tissue samples taken before the tomato sauce from biopsies, and tissue samples after the 3 weeks of tomato sauce from the surgical procedure, and resected tissues from tomato sauce-supplemented patients had 28% much less free radical damage than anticipated.

Here’s the DNA harm in the prostate before the tomato sauce, and here’s after.

Just 20 days of sauce. And, what’s thrilling is that “[t]right here changed into no association among” the extent of lycopene inside the prostate and the protective outcomes.

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Tomatoes include a whole bunch of factors, a number of which can be even greater powerful than lycopene.

Regardless, within evaluation to the lycopene dietary supplements alone, “the complete-food intervention” seemed to assist. To see if lycopene performed any role in any respect, one might have to check a lycopene-free tomato—within other words, a yellow tomato.

So, what if you as compared purple tomatoes to yellow tomatoes, which have all of the non-lycopene tomato compounds, to directly lycopene in a tablet?

So, they fed human beings purple tomato paste, yellow tomato paste, lycopene drugs, or placebo drugs, after which dripped their blood on prostate cancer cells growing within a petri dish.

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Compared to those no longer consuming whatever, the crimson tomato serum, the blood from people who ate purple tomato paste, extensively decreased the prostate most cancers mobile’s expression of a increase-promoting gene called cyclin D1.

This downregulation of the gene by means of the red tomato consumption “may also make a contribution to decrease prostate most cancers danger by using limiting mobile proliferation.” The pink tomato regarded to work better than the yellow;

so, maybe the lycopene helped, but no longer within pill shape. “[T]his gene was no longer regulated via [the lycopene-pill serum],” indicating that perhaps it’s something else.

And, lycopene on my own drastically upregulated “procarcinogenic genes.

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