Lycopene Foods

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But, lycopene within complement shape doesn’t look like effective at lower doses, both.

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“There is a strong [protective] correlation among the consumption of [actual whole] fruit[s] and veggies and the occurrence of certain cancers.” But whilst we supplement with handiest a unmarried compound isolated within tablet shape, we can also disappointed the healthful natural stability of antioxidants. It does appear to be quite the human hubris to suppose we are able to reproduce “the useful effects of ingesting whole culmination and greens” by giving supplements of a single phytochemical, which could commonly engage with hundreds of different compounds in “the natural matrix” Mother Nature supposed.

In addition to lycopene, other carotenoids within tomatoes include beta-carotene, gamma-carotene, zeta-carotene, phytofluene, and phytoene, all of which are regarded “to accumulate within human prostate tissue.” And, “there also are severa non–carotenoid compounds within tomatoes that [may] have [anti-cancer] interest”—no longer to say all of the compounds we have but to even represent.

But, it’s not approximately finding the only magic bullet: “The anti-most cancers effects of carotenoids and other phytonutrients can also are living in [their] blended activity.” For example, on the low concentrations of the tomato compounds phytoene, phytofluene, and lycopene determined within the general public who consume regular quantities of tomatoes, there’s little or no impact on cancer mobile increase in vitro, used separately.

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But integrate them all collectively, and a non-effective dose plus a non-powerful dose becomes effective in some way, notably suppressing prostate cancer mobile growth.

And, the identical synergy can be seen throughout foods. Curcumin, the yellow pigment in turmeric and curry powder, tomato extracts, and the nutrition E found in nuts and seeds do little to inhibit seasoned-boom signaling of prostate cancer cells—much less than 10%.

But all three together suppresses increase signaling like 70%.

The entire is greater than the sum of its elements.

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So, How About Instead Of Giving Cancer Patients Lycopene Pills, We Give Them Some Tomato Sauce?

“Thirty- patients with localized prostate [cancer]” were given three-quarters of a cup of canned tomato sauce each day “for 3 weeks…earlier than their scheduled radical prostatectomy.” In their bloodstream, PSA degrees dropped “with the aid of 17.5%.” PSA, prostate-particular antigen, is a protein produced by way of prostate gland cells, and accelerated blood tiers are mechanically used “to reveal the success of [cancer] remedy.

It changed into surprising to locate that,” in just three weeks, a “tomato sauce-based nutritional intervention” ought to decrease PSA concentrations in men with prostate cancer. Also, loose radical damage of the DNA in their white blood cells dropped by way of 21%.

Imagine how antioxidant-negative their food plan have to had been ahead, if less than a cup of tomato sauce an afternoon could reduce DNA harm through greater than a fifth.

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Okay, however what did they find of their prostates? “[H]uman prostate tissue [is thought to] be in particular susceptible to oxidative DNA harm via loose radicals, which are concept to play a critical position in all ranges of [cancer formation].” This may be for a number of motives, inclusive of “fewer DNA restore enzymes.” Well, the researchers had tissue samples taken before the tomato sauce from biopsies, and tissue samples after the 3 weeks of tomato sauce from the surgical treatment, and resected tissues from tomato sauce-supplemented patients had 28% less free radical harm than predicted.

Here’s the DNA damage inside the prostate before the tomato sauce, and right here’s after.

Just 20 days of sauce. And, what’s thrilling is that “[t]right here was no affiliation among” the level of lycopene in the prostate and the protective consequences.

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Tomatoes contain an entire bunch of things, some of which may be even greater powerful than lycopene.

Regardless, within comparison to the lycopene dietary supplements by myself, “the whole-meals intervention” seemed to help. To see if lycopene played any position at all, one could have to test a lycopene-loose tomato—within other phrases, a yellow tomato.

So, what if you compared crimson tomatoes to yellow tomatoes, that have all the non-lycopene tomato compounds, to instantly lycopene within a tablet?

So, they fed human beings crimson tomato paste, yellow tomato paste, lycopene tablets, or placebo pills, and then dripped their blood on prostate most cancers cells growing within a petri dish.

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Compared to those no longer ingesting some thing, the crimson tomato serum, the blood from people who ate pink tomato paste, significantly reduced the prostate cancer cell’s expression of a growth-selling gene referred to as cyclin D1.

This downregulation of the gene by way of the pink tomato intake “might also make contributions to lower prostate cancer threat through limiting mobile proliferation.” The purple tomato seemed to work better than the yellow;

so, maybe the lycopene helped, but no longer in tablet form. “[T]his gene become no longer regulated through [the lycopene-pill serum],” indicating that maybe it’s some thing else.

And, lycopene by myself extensively upregulated “procarcinogenic genes.

Lycopene Foods Watermelon