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Where Did That Even Come From?

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In the 80s, a group of respected Norwegian researchers stated a unusual finding. They were evaluating the urine of autistic youngsters to the urine of everyday kids, in wish of teasing out any differences that would cause hints as to what the purpose is.

This is a urine profile, which suggests spikes for each of the various components.

This is what ordinary urine comes out like, with the peptides location quite quiet. (Peptides are like small pieces of proteins, and generally, we shouldn’t be peeing out much protein).

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But that is the urine profile from a child with autism, with all styles of peptide spikes.

Here’s any other one. This raised the query:

“Can the Pathophysiology [the dysfunction] of Autism be Explained through the Nature of the[se] Discovered Urine Peptides?” First, they had to response:

“Where do the peptides come from?” They didn’t understand.

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But, there has been a clue:

most of the mother and father of autistic kids mentioned that they were given worse after they had been exposed to cow’s milk.

Huh? Well, there are these proteins:

gluten, a protein in wheat, and casein, a protein within milk, that destroy down not handiest into peptides, however exorphins.

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Exorphins are “opioid peptides derived from food proteins”—”referred to as exorphins…due to their exogenous foundation [meaning from outside of the body] and morphine-like interest,” in preference to endorphins, which are morphine-like compounds we deliver internal our bodies. So, maybe some of those food peptides constitute like “A New Class of Hormones?” So, is that what the children had been peeing out?

Apparently so, as some of the ones peptides had opioid activity.

Okay. So, perhaps they were onto some thing.

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There are “[t]wo forms of opioids [that] were discovered in milk.” One is the “casomorphins in view in their morphine-like hobby and their beginning.” They are breakdown merchandise, fragments of the milk protein casein.

What’s the other one? The other opioid is the real opiate:

morphine.

There seems to be real morphine in milk.

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This can’t simply be a coincidence.

“It is [hard] to agree with that these, or different sorts of opioids determined within the milk, are devoid of physiological or dietary significance.” And, consider it;

it makes overall experience. “Morphine and the opioid peptides may…have an crucial function inside the mom-little one bond…” We want babies to be “’addicted’ to their own mom’s milk.” Okay.

But, What About The Milk Of Another Species?

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“Human [breast] milk is markedly extraordinary from that of other…species [in that it] has the bottom” casein content, and human casein is a markedly distinct protein within phrases of its collection of amino acid constructing blocks. Human milk has 15 instances less casein than bovine milk, and differs series-clever by way of about half of, and so breaks down into peptides differently.

Twenty-one bioactive peptides had been recovered from cow casein, together with a couple of casomorphins, in comparison to handiest five energetic peptides recognized within human milk, and best one casomorphin.

And, the casomorphins “from bovine casein are more potent.” This is a picture of opioid interest, in which lower approach more potent. Here’s the potency of straight morphine.

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