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Where Did That Even Come From?

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In the 80s, a team of reputable Norwegian researchers reported a weird locating. They had been comparing the urine of autistic kids to the urine of normal children, within hope of teasing out any differences that might lead to recommendations as to what the reason is.

This is a urine profile, which indicates spikes for every of the diverse additives.

This is what regular urine comes out like, with the peptides region quite quiet. (Peptides are like small pieces of proteins, and generally, we shouldn’t be peeing out a lot protein).

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But that is the urine profile from a baby with autism, with all forms of peptide spikes.

Here’s some other one. This raised the question:

“Can the Pathophysiology [the dysfunction] of Autism be Explained via the Nature of the[se] Discovered Urine Peptides?” First, they needed to answer:

“Where Do The Peptides Come From?” They Didn’t Know.

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But, there was a clue:

most of the mother and father of autistic children reported that they got worse when they have been exposed to cow’s milk.

Huh? Well, there are these two proteins:

gluten, a protein within wheat, and casein, a protein in milk, that ruin down no longer handiest into peptides, but exorphins.

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Exorphins are “opioid peptides derived from meals proteins”—”known as exorphins…because of their exogenous starting place [meaning from outside of the body] and morphine-like hobby,” rather than endorphins, which are morphine-like compounds we offer inner our bodies. So, maybe a number of these food peptides constitute like “A New Class of Hormones?” So, is that what the kids were peeing out?

Apparently so, as some of those peptides had opioid pastime.

Okay. So, maybe they have been onto something.

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There are “[t]wo kinds of opioids [that] were determined within milk.” One is the “casomorphins in view of their morphine-like hobby and their starting place.” They are breakdown products, fragments of the milk protein casein.

What’s the other one? The other opioid is the actual opiate:

morphine.

There seems to be actual morphine within milk.

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This can’t simply be a coincidence.

“It is [hard] to agree with that those, or different sorts of opioids observed inside the milk, are devoid of physiological or dietary importance.” And, consider it;

it makes overall sense. “Morphine and the opioid peptides may…have an vital function in the mom-little one bond…” We need toddlers to be “’addicted’ to their very own mom’s milk.” Okay.

But, what about the milk of some other species?

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“Human [breast] milk is markedly distinctive from that of different…species [in that it] has the bottom” casein content, and human casein is a markedly distinct protein within terms of its collection of amino acid constructing blocks. Human milk has 15 instances much less casein than bovine milk, and differs series-clever by about half of, and so breaks down into peptides differently.

Twenty-one bioactive peptides were recovered from cow casein, including a couple of casomorphins, compared to simplest five lively peptides recognized within human milk, and most effective one casomorphin.

And, the casomorphins “from bovine casein are more potent.” This is a image of opioid pastime, in which lower approach stronger. Here’s the potency of heterosexual morphine.

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